The abuse of odds ratios and psychosis.

Repeat a hundred times: correlation is not causation. The odds ratios look good. But the rate of serious mental illness (Schizophrenia, Bipolar and schizoaffective disorder) was 50/100 000 in this cohort of male conscripts. Most people with low emotional stability (ie, the neurotic) and social immaturity did not develop psychosis. Read More

And now for something completely RocketLab.

I don't have any dollars in RocketLab. It is privately held to date, but it is very typical Kiwi Hi Tech. We like, small, light, carbon fibre... and we hate lawyers, human resources, and trolls telling us what to do. The launch site is at the… Read More

The problems of meta analysis.

Among those who suffer with psychosis, many have but a partial or minimal response to any medication they can tolerate. This has led to trials of multiple adjuvant medications. This meta analysis looks at classes of medications, and notes that the… Read More

The data is against proana. The data is against fat acceptance.

When I last talked about eating disorders one of the registrars asked if obesity counted. I replied it should, but it was not as yet classified in DSM. There are a bunch of people who hate the idea that obesity is a metabolic disorder, and would… Read More

Confounders, observation, caution.

A confounder is a factor, generally not measured a priori, that may be causing an observed correlation but was not measured or allowed for. The usual method to deal with this in observational studies is to correct for as many factors as present using… Read More

Dust and ash follows convergence

The future of medical education worries new graduates. Locally, there are just enough places for house surgeons, and there are still gaps in registrar (advanced training). But the funding for this is central: the state (who fund the health system)… Read More

Three papers, three pictures.

I was putting together a set of slides for teaching tonight and inadvertently ran into some recent data. All these papers are open source, and I will be giving references. The first, by Zhou and others, looks at "left behind children" -- that is… Read More